Water → HCID 22033802, 화합물

HRID 2163519노트

반응식

HRID 2163519 반응식
[C:1]([CH2:4][C:5](=[O:7])[CH3:6])(=[O:3])[CH3:2].C(N(CC)CC)C.[C:15]1([N:21]=[C:22]=[O:23])[CH:20]=[CH:19][CH:18]=[CH:17][CH:16]=1.O>C1C=CC=CC=1>[C:1]([CH:4]([C:5](=[O:7])[CH3:6])[C:22]([NH:21][C:15]1[CH:20]=[CH:19][CH:18]=[CH:17][CH:16]=1)=[O:23])(=[O:3])[CH3:2]

참가 물질

6

반응물 4

HCID 962WaterHCID 7672Phenyl isocyanateHCID 8471TriethylamineHCID 31261Acetylacetone

생성물 1

HCID 22033802HCID 22033802, 화합물수율 73%

시약·촉매·용매 1

HCID 241Benzene용매2회

실험 절차

A mixture of acetylacetone (5 g) and triethylamine (5.2 g) in dry benzene (50 ml) was treated with phenyl isocyanate (6 g) in dry benzene (25 ml). The mixture was stirred for 3 hr at room temperature. Water (50 ml) was then added, the mixture shaken and the water layer separated. The benzene solution was extracted with two further portions (25 ml) of water and the combined aqueous extracts acidified with dilute hydrochloric acid. The product precipitated and was collected by filtration, washed with water and dried. Diacetyl acetanilide (7.0 g, 73%) was obtained as a colourless solid, m.p. 119-121° C.

후처리

  1. stirringthe mixture shaken
  2. customthe water layer separated
  3. extractionThe benzene solution was extracted with two further portions (25 ml) of water
  4. customThe product precipitated
  5. filtrationwas collected by filtration
  6. washwashed with water
  7. customdried

출처 및 근거

ORD 기록
ord-f461f0e1bcd84d2082fefe54d3d0ce03
출처 데이터셋
uspto-grants-1979_01
특허 번호
US04134987

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