Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Phthalimide → N-methyl-N'-[3-(4-methyl-2-oxazolyl)thiopropyl]thiourea
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Phthalimide | HCID 6809 | — |
| 반응물 | Hydrazine | HCID 9321 | — |
| 반응물 | Methyl isothiocyanate | HCID 11167 | — |
| 반응물 | N-[3-(4-methyl-2-oxazolyl)thiopropyl]thiourea | HCID 86736270 | — |
| 생성물 | N-methyl-N'-[3-(4-methyl-2-oxazolyl)thiopropyl]thiourea | HCID 12923388 | — |
반응 단계
Treatment of the phthalimide compound (3.0 g.) with hydrazine (1.53 g.) followed by reaction of the product directly with methyl isothiocyanate (0.73 g.) using the conditions described in Example 132 afforded N-methyl)-N-[3-(4-methyl-2-oxazolyl)thiopropyl]thiourea (1.0 g.). m.p. 73°-74° (from ethanol-ether-n-hexane).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04137234 |
| 출처 데이터셋 | uspto-grants-1979_01 |
| ORD ID | ord-62fa46014e2640698d84a9d45967b214 |
| 출처 메모 | uspto-grants-1979_01 |