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Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
HRID 2164328생성일: 2026년 10월 26일

Formamide → 6-Amino-5-nitroso-2-pyridin-3-ylpyrimidin-4-ylamine

https://huagongshe.com/reaction/2164328

반응식

참여 물질

역할이름HCID투입량
반응물FormamideHCID 713—
반응물3-PyridinecarboxamidineHCID 202043—
반응물HCID 178508302HCID 178508302—
생성물6-Amino-5-nitroso-2-pyridin-3-ylpyrimidin-4-ylamineHCID 230933—

반응 단계

Taylor et al [J. Am. Chem. Soc. 81, 2442-8 (1959)] show, inter alia, the preparation of 2-(3-pyridinyl)-9H-purin-6-amine by heating the nicotinamidine salt of isonitrosomalonitrile in formamide to produce 4,6-diamino-5-nitroso-2-(3-pyridinyl)pyrimidine and heating the reaction mixture containing said 5-nitroso compound and formamide with a mixture of formic acid and sodium dithionite dihydrate to produce said 2-(3-pyridinyl)-9H-purin-6-amine, for which no use is indicated.

출처 및 근거

DOI10.6084/m9.figshare.5104873.v1
특허 번호US04503228
출처 데이터셋uspto-grants-1985_03
ORD IDord-1b7c567ef25b46b89b1e923bbc04eaef
출처 메모uspto-grants-1985_03