Water → 2-Fluoro-6-(methylamino)benzonitrile
반응식
[F:1][C:2]1[CH:9]=[CH:8][CH:7]=[C:6](F)[C:3]=1[C:4]#[N:5].[CH3:11][NH2:12].O>CN(C=O)C>[F:1][C:2]1[CH:9]=[CH:8][CH:7]=[C:6]([NH:12][CH3:11])[C:3]=1[C:4]#[N:5]참가 물질
5
실험 절차
2,6-Difluorobenzonitrile, 2.78 g (20 mmol) and 5 ml (60 mmol) of 40% aqueous methylamine in 50 ml DMF is stirred at room temperature for 1 hr., poured into water and the product is collected, 2.4 g m.p. 130°-132° C.
후처리
- customthe product is collected
출처 및 근거
- ORD 기록
- ord-d54ade8330034c1ab3d36e8d8ce7f104
- 출처 데이터셋
- uspto-grants-1985_03
- 특허 번호
- US04504660
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