m-Chloroperbenzoic acid → HCID 70478871, 화합물

HRID 2164532노트

반응식

HRID 2164532 반응식
[CH2:1]([S:3][CH2:4][CH:5]=[C:6]1[O:12][CH:11]2[N:8]([C:9](=[O:13])[CH2:10]2)[CH:7]1[C:14]([O:16][CH2:17][C:18]1[CH:23]=[CH:22][CH:21]=[CH:20][CH:19]=1)=[O:15])[CH3:2].ClC1C=CC=C(C(OO)=[O:32])C=1>C(Cl)Cl>[CH2:1]([S:3]([CH2:4][CH:5]=[C:6]1[O:12][CH:11]2[N:8]([C:9](=[O:13])[CH2:10]2)[CH:7]1[C:14]([O:16][CH2:17][C:18]1[CH:19]=[CH:20][CH:21]=[CH:22][CH:23]=1)=[O:15])=[O:32])[CH3:2]

참가 물질

4

반응물 2

HCID 70297m-Chloroperbenzoic acidHCID 70478697HCID 70478697, 화합물

생성물 1

HCID 70478871HCID 70478871, 화합물

시약·촉매·용매 1

HCID 6344Dichloromethane용매

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온도
0 °C

실험 절차

Benzyl 3-(2-ethylthioethylidene)-7-oxo-4-oxa-1-azabicyclo[3,2,0]heptane-2-carboxylate (704 mg) was dissolved in methylene chloride (40 ml) and treated with m-chloroperbenzoic acid (370 mg). The solution was stirred at 0° C. for 1.0 hour and washed with a dilute bicarbonate solution (×2). The extract was dried over MgSO4 and evaporated. Chromatography over silica gel yielded the title product as a mixture of R and S sulphoxides (295 mg);

후처리

  1. washwashed with a dilute bicarbonate solution (×2)
  2. dry with materialThe extract was dried over MgSO4
  3. customevaporated

출처 및 근거

ORD 기록
ord-a9834b1ca0744ebca8c8213808e1b63a
출처 데이터셋
uspto-grants-1985_03
특허 번호
US04505894

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