Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Hydrazine hydrate (1:1) → 6-(4-Chlorophenyl)-4,5-Dihydropyridazin-3(2H)-One
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Hydrazine hydrate (1:1) | HCID 24654 | — |
| 반응물 | 3-(4-Chlorobenzoyl)propionic acid | HCID 77604 | — |
| 용매 | Ethanol | HCID 702 | — |
| 생성물 | 6-(4-Chlorophenyl)-4,5-Dihydropyridazin-3(2H)-One | HCID 120990 | 81.5% |
반응 단계
To a solution of 3-(4-chlorobenzoyl)propionic acid (20 g) in absolute ethanol (200 ml) was added 5 g of hydrazine monohydrate. A thick solid was formed which dissolved after heating. The resulting solution was refluxed for 3 h, cooled and the solid formed filtered and dried to yield 16 g (80%) of 6-(4-chlorophenyl)-4,5-dihydropyridazinone.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05728715 |
| 출처 데이터셋 | uspto-grants-1998_03 |
| ORD ID | ord-0b86b7517ec945ca8eeab9a8c1598395 |
| 출처 메모 | uspto-grants-1998_03 |