3,4-Bis(chloromethyl)pyridine → HCID 86741739, 화합물

HRID 2165054노트

반응식

HRID 2165054 반응식
P(OP(O)=O)(O)=O.C(C(C(C)C)(C(C)C)C(C)C)(C)C.[CH2:21]1[C:29]2[C:25](=[CH:26][C:27]([P:40]([O:46]C(C)C)(=[O:45])[O:41]C(C)C)([P:30]([O:36]C(C)C)(=[O:35])[O:31]C(C)C)[CH:28]=2)[CH:24]=[CH:23][NH:22]1.ClCC1C=NC=CC=1CCl>>[CH2:21]1[C:29]2[C:25](=[CH:26][C:27]([P:30]([OH:35])(=[O:31])[OH:36])([P:40]([OH:46])(=[O:41])[OH:45])[CH:28]=2)[CH:24]=[CH:23][NH:22]1

참가 물질

4

반응물 3

HCID 145187553,4-Bis(chloromethyl)pyridineHCID 86741740HCID 86741740, 화합물HCID 178443211HCID 178443211, 화합물

생성물 1

HCID 86741739HCID 86741739, 화합물

실험 절차

Using the same procedure as in Example VII, tetraisopropyl methane diphosphonate is converted to tetraisopropyl dihydro-2-pyrindine-6,6-diphosphonate by reaction with 3,4-bis(chloromethyl)pyridine. The resulting ester is hydrolyzed as in Example VII to yield the dihydro-2-pyrindine-6,6-diphosphonic acid.

출처 및 근거

ORD 기록
ord-b0abd1bcfa9d496ba941bfc4767b8f86
출처 데이터셋
uspto-grants-1990_07
특허 번호
US04939131

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