3-Aminopyrrolidine → HCID 18640048, 화합물

HRID 2165247노트

반응식

HRID 2165247 반응식
[Cl-:1].[K+].[Pt+2:3].[Cl-:4].[Cl-].[NH2:6][CH:7]1[CH2:11][CH2:10][NH:9][CH2:8]1>O>[Pt+2:3].[Cl:1][C@H:8]1[C@@H:7]([NH2:6])[CH2:11][CH2:10][N:9]1[Cl:4]

참가 물질

4

반응물 2

HCID 1644013-AminopyrrolidineHCID 86744074platinum (II) potassium chloride

생성물 1

HCID 18640048HCID 18640048, 화합물수율 67.9%

시약·촉매·용매 1

HCID 962Water용매

실험 절차

To a solution of platinum (II) potassium chloride, (12.2 g) in water (800 ml) is added (3RS)-3-aminopyrrolidine (2.5 g), and the mixture is stirred at room temperature for 19 hours. The precipitated solid is removed by filtration, and the filtrate is concentrated under reduced pressure. To the residue is added a small amount of water, and the resulting crystals are separated by filtration and washed with water and acetone to give cis-dichloro-(3RS)-3-aminopyrrolidine platinum (II) (6.9 g) as pale yellow crystal.

후처리

  1. customThe precipitated solid is removed by filtration
  2. concentrationthe filtrate is concentrated under reduced pressure
  3. additionTo the residue is added a small amount of water
  4. customthe resulting crystals are separated by filtration
  5. washwashed with water and acetone

출처 및 근거

ORD 기록
ord-dc56a559a44b4b9db7ec1c7bc34f7b37
출처 데이터셋
uspto-grants-1990_07
특허 번호
US04939256

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