Thionyl Chloride → 4-(6-Bromohexyloxy)benzoyl chloride

HRID 2165390노트

반응식

HRID 2165390 반응식
[Br:1][CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][O:8][C:9]1[CH:17]=[CH:16][C:12]([C:13](O)=[O:14])=[CH:11][CH:10]=1.S(Cl)([Cl:20])=O>>[Br:1][CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][O:8][C:9]1[CH:17]=[CH:16][C:12]([C:13]([Cl:20])=[O:14])=[CH:11][CH:10]=1

참가 물질

3

반응물 2

HCID 24386Thionyl ChlorideHCID 20064021HCID 20064021, 화합물

생성물 1

HCID 200639874-(6-Bromohexyloxy)benzoyl chloride

실험 절차

A mixture of 452 g of 4-(6-bromohexyloxy)benzoic acid and 1000 g of thionyl chloride was stirred at room temperature for about 20 hours. The reaction mixture was concentrated in vacuo and residual thionyl chloride removed by repeated addition of toluene and concentration in vacuo. The oily product comprising 4-(6-bromohexyloxy)benzoyl chloride (450 ml) was used directly in the next reaction.

후처리

  1. concentrationThe reaction mixture was concentrated in vacuo and residual thionyl chloride
  2. customremoved
  3. additionaddition of toluene and concentration in vacuo
  4. customThe oily product comprising 4-(6-bromohexyloxy)benzoyl chloride (450 ml) was used directly in the next reaction

출처 및 근거

ORD 기록
ord-b57962b008124058811d7136199c57ea
출처 데이터셋
uspto-grants-1990_07
특허 번호
US04939267

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