Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Potassium Carbonate → N-benzoyl-N'-t-butyl-N'-(ethoxycarbonyl)methylhydrazine
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Potassium Carbonate | HCID 11430 | — |
| 반응물 | 1-Acetoxy-2-bromoethane | HCID 13564 | — |
| 반응물 | N'-tert-butylbenzohydrazide | HCID 299436 | — |
| 용매 | Water | HCID 962 | — |
| 용매 | Diethyl Ether | HCID 3283 | — |
| 용매 | Dimethylformamide | HCID 6228 | — |
| 생성물 | N-benzoyl-N'-t-butyl-N'-(ethoxycarbonyl)methylhydrazine | HCID 15452013 | 9.4% |
반응 단계
N'-t-butyl-N-benzoylhydrazine (2.0 g), powdered potassium carbonate (5 g) and bromoethyl acetate (1.6 g) were stirred in dimethylformamide (20 ml) at 60° C. for 14 hours. The reaction mixture was diluted with water and ether, and the organic layer was separated. The organic layer was washed several times with water, dried over magnesium sulfate and rotavapped to afford an oil. Chromatographic purification gave the pure oil product (0.25 g).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05424333 |
| 출처 데이터셋 | uspto-grants-1995_06 |
| ORD ID | ord-037e49102d464965acd586fc010b4458 |
| 출처 메모 | uspto-grants-1995_06 |