HCID 86627645, 화합물 → HCID 86627646, 화합물
반응식
[Cl:1]C(OC([N:7]1[CH2:12][CH:11]=[C:10]([C:13]2[CH:18]=[C:17]([Cl:19])[CH:16]=[CH:15][C:14]=2[NH:20][C:21]([C:23]2[CH:28]=[CH:27][N:26]=[C:25]([Cl:29])[CH:24]=2)=[O:22])[CH2:9][CH2:8]1)=O)C>CO>[ClH:1].[Cl:29][C:25]1[CH:24]=[C:23]([CH:28]=[CH:27][N:26]=1)[C:21]([NH:20][C:14]1[CH:15]=[CH:16][C:17]([Cl:19])=[CH:18][C:13]=1[C:10]1[CH2:11][CH2:12][NH:7][CH2:8][CH:9]=1)=[O:22]참가 물질
3
실험 절차
Crude 4-{5-chloro-2-[(2-chloro-pyridine-4-carbonyl)-amino]phenyl}-3,6-dihydro-2H-pyridine-1-carboxylic acid 1-chloro-ethyl ester (550 mg) was dissolved in methanol (25 ml) in and heated to reflux for 16 hours. Evaporation afforded the crude title product (465 mg). Retention Time HPLC 1.48 min; MS (ES+) 350, 348 (M+H+).
후처리
- temperatureheated
- temperatureto reflux for 16 hours
- customEvaporation