Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Dimethylformamide diethylacetal → 7-benzyl-octahydro-5H,9bH-2a,4a,7,9a-tetraazacycloocta[cd]pentalene
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Dimethylformamide diethylacetal | HCID 70913 | — |
| 반응물 | 1-Benzyl-1,4,7,10-tetraazacyclododecane | HCID 10084082 | — |
| 용매 | Benzene | HCID 241 | — |
| 생성물 | 7-benzyl-octahydro-5H,9bH-2a,4a,7,9a-tetraazacycloocta[cd]pentalene | HCID 10967659 | 96% |
반응 단계
A solution of 1-benzyl-1,4,7,10-tetraazacyclododecane (4 g; 0.015 mol) and dimethylformamide diethylacetal (6.88 g; 0.0467 mol) in benzene (40 ml) is heated at 80 C. and the azeotropic mixture ethanol-benzene is distilled away. When the conversion is ended, the solvent is evaporated under reduced pressure and the final product is obtained as a yellow oil (4.0 g). Yield 96%
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05424423 |
| 출처 데이터셋 | uspto-grants-1995_06 |
| ORD ID | ord-45ff071bbebe4e44a0b56ce40e0262de |
| 출처 메모 | uspto-grants-1995_06 |