Allyl 2,2,2-Trichloroacetimidate → benzyloxycarbonyl-beta-(allylamino)-L-alanine, methyl ester

HRID 21686

반응식

HRID 21686 반응식
[CH2:1]([O:8][C:9]([NH:11][C@H:12]([C:15]([O:17][CH3:18])=[O:16])[CH2:13][NH2:14])=[O:10])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.ClC(Cl)(Cl)C(=N)O[CH2:23][CH:24]=[CH2:25]>>[CH2:1]([O:8][C:9]([NH:11][C@H:12]([C:15]([O:17][CH3:18])=[O:16])[CH2:13][NH:14][CH2:25][CH:24]=[CH2:23])=[O:10])[C:2]1[CH:3]=[CH:4][CH:5]=[CH:6][CH:7]=1

참가 물질

3

반응물 2

HCID 316905Allyl 2,2,2-TrichloroacetimidateHCID 110432213-Amino-N-((phenylmethoxy)carbonyl)-L-alanine methyl ester

생성물 1

HCID 131719024benzyloxycarbonyl-beta-(allylamino)-L-alanine, methyl ester

실험 절차

The β-amino functionality of Nα -(benzyloxycarbonyl)-β-(amino)-L-alanine, methyl ester is then allylated with allyl trichloroacetimidate to give the corresponding Nα -(benzyloxycarbonyl)-β-(allylamino)-L-alanine, methyl ester using conditions described previously in Scheme D, step b.

출처 및 근거

ORD 기록
ord-84a7ed8818e24215aae5c574a9a88553
출처 데이터셋
uspto-grants-1995_06
특허 번호
US05424425

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