[1-(2,5-Dichlorophenyl)-cyclopentyl]-methanol → (1-Naphthalen-2-yl-cyclopentyl)-methanol

반응식

[CH:1]1[C:10]2[C:5](=[CH:6][CH:7]=[CH:8][CH:9]=2)[CH:4]=[CH:3][C:2]=1[C:11]1([CH:16]=[O:17])[CH2:15][CH2:14][CH2:13][CH2:12]1.ClC1C=CC(Cl)=CC=1C1(CO)CCCC1>>[CH:1]1[C:10]2[C:5](=[CH:6][CH:7]=[CH:8][CH:9]=2)[CH:4]=[CH:3][C:2]=1[C:11]1([CH2:16][OH:17])[CH2:15][CH2:14][CH2:13][CH2:12]1

참가 물질

반응물 2

HCID 86725895[1-(2,5-Dichlorophenyl)-cyclopentyl]-methanol

HCID 867259071-Naphthalen-2-yl-cyclopentanecarbaldehyde

생성물 1

HCID 86725908(1-Naphthalen-2-yl-cyclopentyl)-methanol수율 99%

실험 절차

(1-Naphthalen-2-yl-cyclopentyl)-methanol (213) (22.0 g, crude) was synthesized as a colourless liquid from 1-naphthalen-2-yl-cyclopentanecarbaldehyde (212) (22.0 g, 98.21 mmol) following the procedure described for 1-(2,5-dichlorophenyl)-cyclopentane-methanol (200).

출처 및 근거

ORD 기록: ord-c274091f23d3449a9ef93bd1750e23cb
출처 데이터셋: uspto-grants-2015_06
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US09045486B2

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