2-[1-(2,5-Dichlorophenyl)-cyclopentyl]-acetamidine hydrochloride → 2-(1-Naphthalen-2-yl-cyclopentyl)-acetamidine hydrochloride

HRID 2169260노트

반응식

HRID 2169260 반응식
[CH:1]1[C:10]2[C:5](=[CH:6][CH:7]=[CH:8][CH:9]=2)[CH:4]=[CH:3][C:2]=1[C:11]1([CH2:16][C:17]#[N:18])[CH2:15][CH2:14][CH2:13][CH2:12]1.Cl.[Cl:20]C1C=CC(Cl)=CC=1C1(CC(N)=[NH:35])CCCC1>>[ClH:20].[CH:1]1[C:10]2[C:5](=[CH:6][CH:7]=[CH:8][CH:9]=2)[CH:4]=[CH:3][C:2]=1[C:11]1([CH2:16][C:17]([NH2:35])=[NH:18])[CH2:15][CH2:14][CH2:13][CH2:12]1

참가 물질

3

반응물 2

HCID 867258982-[1-(2,5-Dichlorophenyl)-cyclopentyl]-acetamidine hydrochlorideHCID 86725910(1-Naphthalen-2-yl-cyclopentyl)-acetonitrile

생성물 1

HCID 867259112-(1-Naphthalen-2-yl-cyclopentyl)-acetamidine hydrochloride

실험 절차

2-(1-Naphthalen-2-yl-cyclopentyl)-acetamidine hydrochloride (216) (5.0 g, crude) was synthesized as a white solid from (1-naphthalen-2-yl-cyclopentyl)-acetonitrile (215) (5.0 g, 21.27 mmol) following the procedure described for the HCl-salt of 2-[1-(2,5-dichlorophenyl)-cyclopentyl]-acetamidine hydrochloride (203).

출처 및 근거

ORD 기록
ord-bf7c41fc323f480a8aa230ff6095a5d0
출처 데이터셋
uspto-grants-2015_06
특허 번호
US09045486B2

반응 노트

불러오는 중…