Methanesulfonic acid 1-(4-trifluoromethyl-phenyl)-cyclopentylmethyl ester → (1-(3-(Trifluoromethyl)phenyl)cyclopentyl)methyl methanesulfonate

HRID 2169497노트

반응식

HRID 2169497 반응식
[F:1][C:2]([F:17])([F:16])[C:3]1[CH:4]=[C:5]([C:9]2([CH2:14][OH:15])[CH2:13][CH2:12][CH2:11][CH2:10]2)[CH:6]=[CH:7][CH:8]=1.FC(F)(F)C1C=CC(C2(C[O:32][S:33]([CH3:36])(=O)=[O:34])CCCC2)=CC=1>>[CH3:36][S:33]([O:15][CH2:14][C:9]1([C:5]2[CH:6]=[CH:7][CH:8]=[C:3]([C:2]([F:16])([F:17])[F:1])[CH:4]=2)[CH2:13][CH2:12][CH2:11][CH2:10]1)(=[O:34])=[O:32]

참가 물질

3

반응물 2

HCID 86725929Methanesulfonic acid 1-(4-trifluoromethyl-phenyl)-cyclopentylmethyl esterHCID 86726118(1-(3-(Trifluoromethyl)phenyl)cyclopentyl)methanol

생성물 1

HCID 86726119(1-(3-(Trifluoromethyl)phenyl)cyclopentyl)methyl methanesulfonate

실험 절차

(1-(3-(Trifluoromethyl)phenyl)cyclopentyl)methyl methanesulfonate (471) was synthesized from ((1-(3-(trifluoromethyl)phenyl)cyclopentyl)methanol (470) following the procedure described for methanesulfonic acid 1-(4-trifluoromethyl-phenyl)-cyclopentylmethyl ester (240).

출처 및 근거

ORD 기록
ord-28a26945f1854ee7b7bb57b292ded9ad
출처 데이터셋
uspto-grants-2015_06
특허 번호
US09045486B2

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