2-(1-(3,4-Dichlorophenyl)cyclopentyl)acetonitrile → 2-(1-(3,4-Dichlorophenyl)-cyclopentyl)-acetamidine hydrochloride

HRID 2169508노트

반응식

HRID 2169508 반응식
[Cl:1][C:2]1[CH:3]=[C:4]([C:9]2([CH2:14][C:15]#[N:16])[CH2:13][CH2:12][CH2:11][CH2:10]2)[CH:5]=[CH:6][C:7]=1[Cl:8].Cl.FC(F)(F)C1C=CC(C2(CC(N)=[NH:33])CCCC2)=CC=1>>[ClH:1].[Cl:1][C:2]1[CH:3]=[C:4]([C:9]2([CH2:14][C:15]([NH2:33])=[NH:16])[CH2:13][CH2:12][CH2:11][CH2:10]2)[CH:5]=[CH:6][C:7]=1[Cl:8]

참가 물질

3

반응물 2

HCID 867261282-(1-(3,4-Dichlorophenyl)cyclopentyl)acetonitrileHCID 867261312-[1-(4-Trifluoromethyl-phenyl)-cyclopentyl]-acetamidine hydrochloride

생성물 1

HCID 867261292-(1-(3,4-Dichlorophenyl)-cyclopentyl)-acetamidine hydrochloride

실험 절차

2-(1-(3,4-Dichlorophenyl)-cyclopentyl)-acetamidine hydrochloride (486) was synthesized from 2-(1-(3,4-dichlorophenyl)cyclopentyl)acetonitrile (485) following the procedure described for the HCl-salt of 2-[1-(4-trifluoromethyl-phenyl)-cyclopentyl]-acetamidine hydrochloride (242).

출처 및 근거

ORD 기록
ord-e45719bf690844fc83f1dab0daf28b87
출처 데이터셋
uspto-grants-2015_06
특허 번호
US09045486B2

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