HCID 178457472, 화합물 → HCID 178457436, 화합물

HRID 2169531노트

반응식

HRID 2169531 반응식
OCCN(C)C(C1C(OCC2C=CC=CC=2)=C(O)N=C(CC2(C3C4C(=CC=CC=4)C=CC=3)CCCC2)N=1)=O.[CH2:39]([O:46][C:47]1[C:48]([C:70]([N:72]([CH2:76][CH2:77][O:78][Si](C(C)(C)C)(C)C)[CH:73]([CH3:75])[CH3:74])=[O:71])=[N:49][C:50]([CH2:54][C:55]2([C:60]3[C:69]4[C:64](=[CH:65][CH:66]=[CH:67][CH:68]=4)[CH:63]=[CH:62][CH:61]=3)[CH2:59][CH2:58][CH2:57][CH2:56]2)=[N:51][C:52]=1[OH:53])[C:40]1[CH:45]=[CH:44][CH:43]=[CH:42][CH:41]=1>>[CH2:39]([O:46][C:47]1[C:48]([C:70]([N:72]([CH2:76][CH2:77][OH:78])[CH:73]([CH3:75])[CH3:74])=[O:71])=[N:49][C:50]([CH2:54][C:55]2([C:60]3[C:69]4[C:64](=[CH:65][CH:66]=[CH:67][CH:68]=4)[CH:63]=[CH:62][CH:61]=3)[CH2:56][CH2:57][CH2:58][CH2:59]2)=[N:51][C:52]=1[OH:53])[C:40]1[CH:41]=[CH:42][CH:43]=[CH:44][CH:45]=1

참가 물질

3

반응물 2

HCID 178457472HCID 178457472, 화합물HCID 178484637HCID 178484637, 화합물

생성물 1

HCID 178457436HCID 178457436, 화합물

실험 절차

This compound was prepared following the same method as described for 5-benzyloxy-6-hydroxy-2-(1-naphthalen-1-yl-cyclopentylmethyl)-pyrimidine-4-carboxylic acid (2-hydroxyethyl)-methyl-amide (351) from 5-(benzyloxy)-N-(2-((tert-butyldimethylsilyl)oxy)ethyl)-6-hydroxy-N-isopropyl-2-((1-(naphthalen-1-yl)cyclopentyl)methyl)pyrimidine-4-carboxamide (510).

후처리

  1. customThis compound was prepared

출처 및 근거

ORD 기록
ord-55cc3745f4ba49648abedb481b63b081
출처 데이터셋
uspto-grants-2015_06
특허 번호
US09045486B2

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