9-benzyloxy-6-(1-naphthalen-1-yl-cyclopentylmethyl)-3,4-dihydro-2H-pyrazino[1,2-c]pyrimidine-1,8-dione → 9-(Benzyloxy)-6-((1-(4-chlorophenyl)cyclopentyl)methyl)-3,4-dihydro-1H-pyrazino[1,2-c]pyrimidine-1,8(2H)-dione
반응식
C(OC1C(=O)N=C(CC2(C3C4C(=CC=CC=4)C=CC=3)CCCC2)N2CCNC(=O)C=12)C1C=CC=CC=1.[CH2:37]([O:44][C:45]1[C:46]([C:65]([NH:67][CH2:68][CH2:69]O)=[O:66])=[N:47][C:48]([CH2:52][C:53]2([C:58]3[CH:63]=[CH:62][C:61]([Cl:64])=[CH:60][CH:59]=3)[CH2:57][CH2:56][CH2:55][CH2:54]2)=[N:49][C:50]=1[OH:51])[C:38]1[CH:43]=[CH:42][CH:41]=[CH:40][CH:39]=1>>[CH2:37]([O:44][C:45]1[C:50](=[O:51])[N:49]=[C:48]([CH2:52][C:53]2([C:58]3[CH:63]=[CH:62][C:61]([Cl:64])=[CH:60][CH:59]=3)[CH2:57][CH2:56][CH2:55][CH2:54]2)[N:47]2[CH2:69][CH2:68][NH:67][C:65](=[O:66])[C:46]=12)[C:38]1[CH:43]=[CH:42][CH:41]=[CH:40][CH:39]=1참가 물질
3
실험 절차
This compound was prepared following the same method as described for pure 9-benzyloxy-6-(1-naphthalen-1-yl-cyclopentylmethyl)-3,4-dihydro-2H-pyrazino[1,2-c]pyrimidine-1,8-dione (348) from 5-(benzyloxy)-2-((1-(4-chlorophenyl)cyclopentyl)methyl)-6-hydroxy-N-(2-hydroxyethyl)pyrimidine-4-carboxamide (515).
후처리
- custom