3,4-Difluorobenzyl alcohol → HCID 86728416, 화합물

반응식

[F:1][C:2]1[CH:3]=[C:4]([CH2:9][OH:10])[CH:5]=[CH:6][C:7]=1[F:8].Cl[C:12]1[CH:13]=[C:14]2[N:21]([CH:22]3[CH2:24][CH2:23]3)[CH2:20][CH2:19][N:15]2[C:16](=[O:18])[N:17]=1>>[CH:22]1([N:21]2[C:14]3[N:15]([C:16](=[O:18])[N:17]=[C:12]([O:10][CH2:9][C:4]4[CH:5]=[CH:6][C:7]([F:8])=[C:2]([F:1])[CH:3]=4)[CH:13]=3)[CH2:19][CH2:20]2)[CH2:24][CH2:23]1

참가 물질

반응물 2

HCID 5228333,4-Difluorobenzyl alcohol

HCID 86728325HCID 86728325, 화합물

생성물 1

HCID 86728416HCID 86728416, 화합물

실험 절차

The title compound was prepared by a procedure similar to that described for E9 starting from (3,4-difluorophenyl)methanol and 7-chloro-1-cyclopropyl-2,3-dihydroimidazo[1,2-c]pyrimidin-5(1H)-one.

출처 및 근거

ORD 기록: ord-51968ab141c64436b5173a26d5adca7d
출처 데이터셋: uspto-grants-2015_06
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US09051325B2

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