Methanol → HCID 596025, 화합물

HRID 2171949노트

반응식

HRID 2171949 반응식
[N+:1]([C:4]1[C:9]([CH3:10])=[C:8]([CH3:11])[C:7]([CH3:12])=[C:6]([CH3:13])[C:5]=1[CH3:14])([O-])=O.CO.[Cl-].[NH4+]>[Zn].O>[CH3:10][C:9]1[C:4]([NH2:1])=[C:5]([CH3:14])[C:6]([CH3:13])=[C:7]([CH3:12])[C:8]=1[CH3:11]

참가 물질

6

반응물 3

HCID 887MethanolHCID 25517Ammonium ChlorideHCID 518726Pentamethylnitrobenzene

생성물 1

HCID 596025HCID 596025, 화합물

시약·촉매·용매 2

HCID 23994Zinc촉매HCID 962Water용매

실험 절차

A one neck 2000 ml round bottom flask was charged with 50 grams of 1-nitro-2,3,4,5,6-pentamethylbenzene and 1000 ml methanol. A solution of 50 g of ammonium chloride and 200 ml of water was then added. Zinc dust (50 g) was then added in portions. The mixture was allowed to stir for 20 hours. The solids were filtered and the solvent was removed from the mother liquor. The product was purified by silica gel column with dichlormethane as the eluent. The good fractions are combined to yield pentamethylaniline as a white solid.

후처리

  1. filtrationThe solids were filtered
  2. customthe solvent was removed from the mother liquor
  3. customThe product was purified by silica gel column with dichlormethane as the eluent

출처 및 근거

ORD 기록
ord-3df678bd394642c886b9ed5a720c44fa
출처 데이터셋
uspto-grants-2015_06
특허 번호
US09051344B2

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