Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Bromine → 2-Amino-5-bromonicotinaldehyde hydrobromide
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Bromine | HCID 24408 | — |
| 반응물 | 3-Pyridinecarboxaldehyde, 2-amino- | HCID 737633 | — |
| 용매 | Acetic Acid | HCID 176 | — |
| 생성물 | 2-Amino-5-bromonicotinaldehyde hydrobromide | HCID 86606146 | 165.3% |
반응 단계
A solution of bromine (1.05 mL, 20.0 mmol) in acetic acid (20 mL) was added to a solution of 2-amino-3-pyridinecarboxaldehyde (2.5 g, 20 mmol) in acetic acid (50 mL) at room temperature. The reaction mixture was then stirred overnight. The resulting precipitate was filtered and washed with diethyl ether to give the title compound as a white solid (4.66 g, 80%).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US09051321B2 |
| 출처 데이터셋 | uspto-grants-2015_06 |
| ORD ID | ord-004bfe9f392342fab47f97a990d27bd0 |
| 출처 메모 | uspto-grants-2015_06 |