Tert-butyl (1-oxo-1,3-dihydro-2-benzofuran-5-yl)acetate → (1-Oxo-1,3-dihydro-2-benzofuran-5-yl)acetic acid
반응식
[O:1]=[C:2]1[C:6]2[CH:7]=[CH:8][C:9]([CH2:11][C:12]([O:14]C(C)(C)C)=[O:13])=[CH:10][C:5]=2[CH2:4][O:3]1>C(O)(C(F)(F)F)=O>[O:1]=[C:2]1[C:6]2[CH:7]=[CH:8][C:9]([CH2:11][C:12]([OH:14])=[O:13])=[CH:10][C:5]=2[CH2:4][O:3]1참가 물질
3
실험 절차
tert-Butyl (1-oxo-1,3-dihydro-2-benzofuran-5-yl)acetate (1.2 g, 4.8 mmol) was dissolved in TFA and stirred at room temperature for one h. The reaction mixture was concentrated and pumped under vacuum overnight to afford the title compound. LC-MS (IE, m/z): 193.2 [M+1]+.
후처리
- concentrationThe reaction mixture was concentrated
- custompumped under vacuum overnight
출처 및 근거
- ORD 기록
- ord-c62a8fe2907d4f8b86e5442bd5f96207
- 출처 데이터셋
- uspto-grants-2015_06
- 특허 번호
- US09056859B2
반응 노트
불러오는 중…