(1S,6R)-3,8-Diazabicyclo[4.2.0]octan-8-yl(2-fluoro-6-(2H-1,2,3-triazol-2-yl)phenyl)methanone → (1S,6R)-3,8-Diazabicyclo[4.2.0]octan-8-yl(5-fluoro-2-(2H-1,2,3-triazol-2-yl)phenyl)methanone
반응식
[C@H:1]12[N:8]([C:9]([C:11]3[C:16]([N:17]4[N:21]=[CH:20][CH:19]=[N:18]4)=[CH:15][CH:14]=[CH:13][C:12]=3F)=[O:10])[CH2:7][C@H:6]1[CH2:5][CH2:4][NH:3][CH2:2]2.[F:23]C1C=CC=C(N2N=CC=N2)C=1C(O)=O>>[C@H:1]12[N:8]([C:9]([C:11]3[CH:12]=[C:13]([F:23])[CH:14]=[CH:15][C:16]=3[N:17]3[N:21]=[CH:20][CH:19]=[N:18]3)=[O:10])[CH2:7][C@H:6]1[CH2:5][CH2:4][NH:3][CH2:2]2참가 물질
3
실험 절차
The title compound was prepared in a manner analogous to Intermediate 28, substituting 5-fluoro-6-(2H-1,2,3-triazol-2-yl)benzoic acid for 2-fluoro-6-(2H-1,2,3-triazol-2-yl)benzoic acid. MS (ESI) mass calcd. C15H16FN5O, 301.32; m/z found 302.0 [M+H]+.
출처 및 근거
- ORD 기록
- ord-49a77b3e3d43469aabb0fb499bc57716
- 출처 데이터셋