Ethyl [(2,3-dimethylphenyl)oxy]acetate → 3-(2,3-Dimethylphenyl)propyl 5-bromo-3,4-dihydroquinoline-1(2H)-carboxylate
반응식
[Br:1][C:2]1[CH:11]=[CH:10][CH:9]=[C:8]2[C:3]=1[CH2:4][CH2:5][CH2:6][N:7]2[C:12]([O:14][CH2:15][CH2:16]OC1C=CC=C(C)C=1C)=[O:13].CC1C(C)=CC=CC=1OCC(OCC)=O.[CH3:41][C:42]1[C:47]([CH3:48])=[CH:46][CH:45]=[CH:44][C:43]=1[CH2:49]CC(OC)=O>>[Br:1][C:2]1[CH:11]=[CH:10][CH:9]=[C:8]2[C:3]=1[CH2:4][CH2:5][CH2:6][N:7]2[C:12]([O:14][CH2:15][CH2:16][CH2:49][C:43]1[CH:44]=[CH:45][CH:46]=[C:47]([CH3:48])[C:42]=1[CH3:41])=[O:13]참가 물질
4
실험 절차
The title compound was prepared using a procedure analogous to 2-(2,3-dimethylphenoxy)ethyl 5-bromo-3,4-dihydroquinoline-1(2H)-carboxylate except that ethyl 2-(2,3-dimethylphenoxy)acetate was replaced by methyl 3-(2,3-dimethylphenyl)propanoate. LCMS, [M+Na]+=426.0.
출처 및 근거
- ORD 기록
- ord-6b1966cb2de4456ca4f7dc5a6aca7e08
- 출처 데이터셋
- uspto-grants-2015_06
- 특허 번호
- US09062028B2
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