methyl 3-[(4-bromo-1H-pyrazol-1-yl)methyl]benzoate → 3-((4-bromo-1H-pyrazol-1-yl)methyl)benzoic acid

HRID 2175252노트

반응식

HRID 2175252 반응식
CC1C(C)=CC=CC=1OCCCC(N1C2C(=C(C3C=CN=C(C(OC)=O)C=3)C=CC=2)CCC1)=O.[Br:35][C:36]1[CH:37]=[N:38][N:39]([CH2:41][C:42]2[CH:43]=[C:44]([CH:49]=[CH:50][CH:51]=2)[C:45]([O:47]C)=[O:46])[CH:40]=1>>[Br:35][C:36]1[CH:37]=[N:38][N:39]([CH2:41][C:42]2[CH:43]=[C:44]([CH:49]=[CH:50][CH:51]=2)[C:45]([OH:47])=[O:46])[CH:40]=1

참가 물질

3

반응물 2

HCID 17024610methyl 3-[(4-bromo-1H-pyrazol-1-yl)methyl]benzoateHCID 70982851Methyl 4-(1-(4-(2,3-dimethylphenoxy)butanoyl)-1,2,3,4-tetrahydroquinolin-5-yl)picolinate

생성물 1

HCID 6610343-((4-bromo-1H-pyrazol-1-yl)methyl)benzoic acid

실험 절차

The title compound was prepared using a procedure analogous to Example 2 except that methyl 4-(1-(4-(2,3-dimethylphenoxy)butanoyl)-1,2,3,4-tetrahydroquinolin-5-yl)picolinate was replaced by methyl 3-((4-bromo-1H-pyrazol-1-yl)methyl)benzoate. LCMS, [M+H]+=281.0.

출처 및 근거

ORD 기록
ord-933938a416ce4cb1aa7679e8aa505239
출처 데이터셋
uspto-grants-2015_06
특허 번호
US09062028B2

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