Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
3-Methoxyacetophenone → (+-)-1-(3-Methoxyphenyl)ethanol
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 3-Methoxyacetophenone | HCID 11460 | — |
| 반응물 | Ammonium Chloride | HCID 25517 | — |
| 반응물 | Sodium borohydride | HCID 4311764 | — |
| 용매 | Methanol | HCID 887 | — |
| 생성물 | (+-)-1-(3-Methoxyphenyl)ethanol | HCID 90902 | 86.1% |
반응 단계
To a solution of 3-methoxyacetophenone (3 g; 20 mmol) in methanol (60 mL) is added sodium borohydride (1.13 g; 30 mmol) in four portions over one hour. The reaction is stirred at room temperature overnight, neutralized with saturated ammonium chloride, and extracted with ethyl acetate. The organics are separated, washed with water, and dried over magnesium sulfate. The solvent is removed to give 2.62 grams of 1-(3-methoxyphenyl)-ethanol.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US09067897B2 |
| 출처 데이터셋 | uspto-grants-2015_06 |
| ORD ID | ord-f34503721ede4d6d87a5b746acb3f354 |
| 출처 메모 | uspto-grants-2015_06 |