Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
5-(4-Chlorophenyl)-2-oxo-1,2-dihydropyridine-3-carbonitrile → 5-(4-Chlorophenyl)-2-hydroxypyridine
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 5-(4-Chlorophenyl)-2-oxo-1,2-dihydropyridine-3-carbonitrile | HCID 2763910 | — |
| 용매 | Phosphoric Acid | HCID 1004 | — |
| 생성물 | 5-(4-Chlorophenyl)-2-hydroxypyridine | HCID 10262372 | 75.6% |
반응 단계
A mixture of 3-cyano-5-(4-chlorophenyl)-2-pyridinone (4.6 g) and 85% H3PO4 (60 ml) was heated at reflux for 16 hours. The resulting mixture was cooled to room temperature, poured into ice/water and filtered yielding 3.1 g of 5-(4-chlorophenyl)-2-pyridinone as a yellow solid.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05728715 |
| 출처 데이터셋 | uspto-grants-1998_03 |
| ORD ID | ord-354b2e3cf6af4b84a2f7d3ebed5eb64d |
| 출처 메모 | uspto-grants-1998_03 |