Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Water → (3,6-Dichloropyridazin-4-yl)diethylamine
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Water | HCID 962 | — |
| 반응물 | Diethylamine | HCID 8021 | — |
| 반응물 | Ethyl Acetate | HCID 8857 | — |
| 반응물 | 3,4,6-Trichloropyridazine | HCID 95123 | — |
| 용매 | Toluene | HCID 1140 | — |
| 생성물 | (3,6-Dichloropyridazin-4-yl)diethylamine | HCID 58136930 | — |
반응 단계
3,4,6-Trichloropyridazine (2 g) and diethylamine (2.4 ml) were initially charged in toluene (10 ml) and left to stand at RT for 3 days. Then the mixture was admixed with water and EA, and the EA phase was removed. The EA phase was washed three times with water, dried over magnesium sulfate, filtered and concentrated. The residue was purified using silica gel (70 g cartridge, n-heptane/EA gradient 0-50% within 60 min). 1.1 g of the title compound were obtained.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08198272B2 |
| 출처 데이터셋 | uspto-grants-2012_06 |
| ORD ID | ord-8b427b2e1e5a481394b1b715a71e768f |
| 출처 메모 | uspto-grants-2012_06 |