2-Bromo-5-fluoropyridine → 1-(3-Fluoropyridin-2-yl)-1H-imidazo[4,5-c]pyridine

HRID 2177553노트

반응식

HRID 2177553 반응식
F[C:2]1[CH:3]=[CH:4][C:5]([N:8]2[C:16]3[CH:15]=[CH:14][N:13]=[CH:12][C:11]=3[N:10]=[CH:9]2)=[N:6][CH:7]=1.BrC1C=CC([F:24])=CN=1>>[F:24][C:4]1[C:5]([N:8]2[C:16]3[CH:15]=[CH:14][N:13]=[CH:12][C:11]=3[N:10]=[CH:9]2)=[N:6][CH:7]=[CH:2][CH:3]=1

참가 물질

3

반응물 2

HCID 27831712-Bromo-5-fluoropyridineHCID 904095831-(5-Fluoropyridin-2-yl)-1H-imidazo[4,5-c]pyridine

생성물 1

HCID 904084251-(3-Fluoropyridin-2-yl)-1H-imidazo[4,5-c]pyridine

실험 절차

Intermediate 8 was prepared in a manner analogous to Intermediate 1, substituting 2-bromo-3-fluoropyridine for 2-bromo-5-fluoropyridine. MS (ESI): mass calculated for C11H7FN4, 214.07; m/z found 215.1 [M+H]+.

출처 및 근거

ORD 기록
ord-cb1426f8916b4ca7b589896dfe7baa3c
출처 데이터셋
uspto-grants-2015_06
특허 번호
US09066946B2

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