Aniline → 7-methyl-1-phenyl-1H-[1,2,3]triazolo[4,5-c]pyridine

HRID 2177643노트

반응식

Cl[C:2]1[C:7]([N+:8]([O-])=O)=[CH:6][N:5]=[CH:4][C:3]=1[CH3:11].ClC1C=C[N:16]=CC=1[N+]([O-])=O.[NH2:22][C:23]1[CH:28]=[CH:27][CH:26]=[CH:25][CH:24]=1.NC1C=CC=CN=1>>[CH3:11][C:3]1[C:2]2[N:22]([C:23]3[CH:28]=[CH:27][CH:26]=[CH:25][CH:24]=3)[N:16]=[N:8][C:7]=2[CH:6]=[N:5][CH:4]=1

참가 물질

반응물 4

HCID 6115Aniline

HCID 104392-Aminopyridine

HCID 27357814-Chloro-3-nitropyridine

HCID 588823714-Chloro-3-methyl-5-nitropyridine

생성물 1

HCID 904100647-methyl-1-phenyl-1H-[1,2,3]triazolo[4,5-c]pyridine

실험 절차

The title compound was prepared in a manner analogous to Intermediate 17, Step 1 through Intermediate 19, Step 3 substituting 4-chloro-3-methyl-5-nitro-pyridine for 4-chloro-3-nitropyridine, and aniline for 2-aminopyridine. MS (ESI) mass calcd. C12H10N4, 210.1. m/z found, 225.1 [M+H]+.

출처 및 근거

ORD 기록: ord-c9f68a9b1b97435d892bcb3d42653eeb
출처 데이터셋: uspto-grants-2015_06
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US09066946B2

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