2-Bromoethyl methyl ether → Methyl 6-(benzenesulphonylmethyl)-3-(furan-3-yl)-2-(2-methoxy-ethoxy)benzoate

HRID 2177698노트

반응식

HRID 2177698 반응식
[C:1]1([S:7]([CH2:10][C:11]2[C:16]([C:17]([O:19][CH2:20]C)=[O:18])=[C:15]([O:22][CH2:23][CH2:24]NC(OC(C)(C)C)=O)[C:14]([C:33]3[CH:37]=[CH:36][O:35][CH:34]=3)=[CH:13][CH:12]=2)(=[O:9])=[O:8])[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.C1(S(CC2C([C:54](OC)=[O:55])=C(O)C(C3C=COC=3)=CC=2)(=O)=O)C=CC=CC=1.COCCBr>>[C:1]1([S:7]([CH2:10][C:11]2[C:16]([C:17]([O:19][CH3:20])=[O:18])=[C:15]([O:22][CH2:23][CH2:24][O:55][CH3:54])[C:14]([C:33]3[CH:37]=[CH:36][O:35][CH:34]=3)=[CH:13][CH:12]=2)(=[O:8])=[O:9])[CH:2]=[CH:3][CH:4]=[CH:5][CH:6]=1

참가 물질

4

반응물 3

HCID 809722-Bromoethyl methyl etherHCID 67107565Ethyl 6-(benzenesulphonylmethyl)-2-[2-(t-butoxycarbonyl)aminoethoxy]-3-(furan-3-yl)benzoateHCID 67107618Methyl 6-(benzenesulphonylmethyl)-3-(furan-3-yl)-2-hydroxybenzoate2회

생성물 1

HCID 67107755Methyl 6-(benzenesulphonylmethyl)-3-(furan-3-yl)-2-(2-methoxy-ethoxy)benzoate

실험 절차

Prepared by proceeding in a similar manner to Intermediate 10, starting from methyl 6-(benzenesulphonylmethyl)-3-(furan-3-yl)-2-hydroxybenzoate (Intermediate 114) and 2-bromoethyl methyl ether.

후처리

  1. customPrepared

출처 및 근거

ORD 기록
ord-2bbbd36708af48ef83be8003fd4dca7a
출처 데이터셋
uspto-grants-2015_06
특허 번호
US09067905B2

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