Methyl 3-bromo-6-(3-chlorobenzenesulphonylmethyl)-2-methoxybenzoate → Methyl 3-bromo-6-(3-fluorobenzenesulphonylmethyl)-2-methoxybenzoate

HRID 2177763노트

반응식

HRID 2177763 반응식
[Br:1][C:2]1[C:3]([O:23][CH3:24])=[C:4]([C:9]([CH2:12][S:13]([C:16]2[CH:21]=[CH:20][CH:19]=[C:18](Cl)[CH:17]=2)(=[O:15])=[O:14])=[CH:10][CH:11]=1)[C:5]([O:7][CH3:8])=[O:6].BrC1C(OC)=C(C(CSC2C=CC=C([F:44])C=2)=CC=1)C(OC)=O>>[Br:1][C:2]1[C:3]([O:23][CH3:24])=[C:4]([C:9]([CH2:12][S:13]([C:16]2[CH:21]=[CH:20][CH:19]=[C:18]([F:44])[CH:17]=2)(=[O:15])=[O:14])=[CH:10][CH:11]=1)[C:5]([O:7][CH3:8])=[O:6]

참가 물질

3

반응물 2

HCID 67107903Methyl 3-bromo-6-(3-chlorobenzenesulphonylmethyl)-2-methoxybenzoateHCID 67107924Methyl 3-bromo-6-(3-fluorophenylthiomethyl)-2-methoxybenzoate2회

생성물 1

HCID 67107553Methyl 3-bromo-6-(3-fluorobenzenesulphonylmethyl)-2-methoxybenzoate

실험 절차

Prepared by proceeding in a similar manner to Intermediate 68, starting from methyl 3-bromo-6-(3-fluorophenylthiomethyl)-2-methoxybenzoate (Intermediate 103).

후처리

  1. customPrepared

출처 및 근거

ORD 기록
ord-159f0f564bbe41e8aace962f04cbf2a5
출처 데이터셋
uspto-grants-2015_06
특허 번호
US09067905B2

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