4-Fluorothiophenol → Methyl 3-bromo-6-(4-fluorophenylthiomethyl)-3-methoxybenzoate

HRID 2177781노트

반응식

[Br:1][C:2]1[C:3](OC)=[C:4]([C:10]([CH2:13][S:14][C:15]2[CH:20]=[CH:19][CH:18]=[CH:17][CH:16]=2)=[CH:11][CH:12]=1)[C:5]([O:7][CH2:8]C)=[O:6].BrC1C([O:36][CH3:37])=C(C(CBr)=CC=1)C(OC)=O.[F:38]C1C=CC(S)=CC=1>>[Br:1][C:2]1([O:36][CH3:37])[CH:12]=[CH:11][C:10]([CH2:13][S:14][C:15]2[CH:16]=[CH:17][C:18]([F:38])=[CH:19][CH:20]=2)=[C:4]([C:5]([O:7][CH3:8])=[O:6])[CH2:3]1

참가 물질

반응물 3

HCID 677894-Fluorothiophenol

HCID 66685947Methyl 3-bromo-6-bromomethyl-2-methoxybenzoate2회

HCID 67107500HCID 67107500, 화합물

생성물 1

HCID 67107753Methyl 3-bromo-6-(4-fluorophenylthiomethyl)-3-methoxybenzoate

실험 절차

Prepared by proceeding in a manner similar to Intermediate 73, starting from methyl 3-bromo-6-bromomethyl-2-methoxybenzoate (Intermediate 89) and 4-fluorothiophenol.

후처리

customPrepared

출처 및 근거

ORD 기록: ord-2980e5a516a34cce8efcaed321dc6def
출처 데이터셋: uspto-grants-2015_06
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US09067905B2

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