Methyl 3-bromo-6-(2-hydroxyethylthiomethyl)-2-methoxybenzoate → Methyl 3-bromo-6-(2-hydroxyethanesulphonylmethyl)-2-methoxybenzoate

반응식

[Br:1][C:2]1[C:3]([O:23][CH3:24])=[C:4]([C:9]([CH2:12][S:13]([C:16]2C=CC=C[C:17]=2[OH:22])(=[O:15])=[O:14])=[CH:10][CH:11]=1)[C:5]([O:7][CH3:8])=[O:6].BrC1C(OC)=C(C(CSCCO)=CC=1)C(OC)=O>>[Br:1][C:2]1[C:3]([O:23][CH3:24])=[C:4]([C:9]([CH2:12][S:13]([CH2:16][CH2:17][OH:22])(=[O:15])=[O:14])=[CH:10][CH:11]=1)[C:5]([O:7][CH3:8])=[O:6]

참가 물질

반응물 2

HCID 67107555Methyl 3-bromo-6-(2-hydroxyethylthiomethyl)-2-methoxybenzoate2회

HCID 67107647Methyl 3-bromo-6-(2-hydroxybenzenesulphonylmethyl)-2-methoxybenzoate

생성물 1

HCID 67107820Methyl 3-bromo-6-(2-hydroxyethanesulphonylmethyl)-2-methoxybenzoate

실험 절차

Prepared by proceeding in a similar manner to Intermediate 138, starting from methyl 3-bromo-6-(2-hydroxyethylthiomethyl)-2-methoxybenzoate (Intermediate 174).

후처리

customPrepared

출처 및 근거

ORD 기록: ord-140f799093fb4cc4a4f509a84ed79bf3
출처 데이터셋: uspto-grants-2015_06
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US09067905B2

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