Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Water → 5-Bromopentylphthalimide
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Water | HCID 962 | — |
| 반응물 | 1,5-Dibromopentane | HCID 8100 | — |
| 반응물 | Phthalimide potassium salt | HCID 24194345 | — |
| 용매 | Dimethylformamide | HCID 6228 | — |
| 생성물 | 5-Bromopentylphthalimide | HCID 22352176 | 281.4% |
반응 단계
Potassium phthalimide (5.4 mmoles) was added to a solution of 1,5-dibromopentane (3.72 g; 16.2 mmoles) in dimethylformamide (8 ml) and heated to 80° C. approx. under stirring. After 2 hours, water was added and the solution was repeatedly extracted with ether. The collected organic phases were washed with water, dried on Na2SO4 and evaporated under reduced pressure to give a solid (4.50 g), which was purified by chromatography on silica gel (Etp/Et2O 8:2) yielding 2.38 g of a white solid. Yield 68%.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05424451 |
| 출처 데이터셋 | uspto-grants-1995_06 |
| ORD ID | ord-48a90d782a0f4ad6823194186ca6696b |
| 출처 메모 | uspto-grants-1995_06 |