Sulfuryl chloride → 6-Bromo-8-chloro-7-isopropoxy-2,2-dimethyl-chroman-4-one

HRID 2180460노트

반응식

HRID 2180460 반응식
[Br:1][C:2]1[CH:3]=[C:4]2[C:9](=[CH:10][C:11]=1[O:12][CH:13]([CH3:15])[CH3:14])[O:8][C:7]([CH3:17])([CH3:16])[CH2:6][C:5]2=[O:18].S(Cl)([Cl:22])(=O)=O>ClCCl>[Br:1][C:2]1[CH:3]=[C:4]2[C:9](=[C:10]([Cl:22])[C:11]=1[O:12][CH:13]([CH3:14])[CH3:15])[O:8][C:7]([CH3:16])([CH3:17])[CH2:6][C:5]2=[O:18]

참가 물질

4

반응물 2

HCID 24648Sulfuryl chlorideHCID 224909096-Bromo-7-isopropoxy-2,2-dimethyl-chroman-4-one2회

생성물 1

HCID 224907866-Bromo-8-chloro-7-isopropoxy-2,2-dimethyl-chroman-4-one

시약·촉매·용매 1

HCID 6344Dichloromethane용매

실험 절차

Following General Procedure B, 6-bromo-7-isopropoxy-2,2-dimethyl-chroman-4-one, (Compound 6, 2.2 g, 7.0 mmol) and sulfuryl chloride (0.84 mL, 10.5 mmol) in dichloromethane were reacted to yield the title compound as white trapezoidal plates after recrystallization from hexanes.

후처리

  1. customwere reacted

출처 및 근거

ORD 기록
ord-70fe9f8c19564365a39bda179e28725f
출처 데이터셋
uspto-grants-2005_05
특허 번호
US06887896B1

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