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Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
HRID 2181262생성일: 2026년 10월 27일

4-Chloromethyl-2-(4-isopropyl-phenyl)-thiazole → Rac-2-ethoxy-3-{1-[2-(4-isopropyl-phenyl)-thiazol-4-ylmethyl]-1h-indol-6-yl}-propionic acid

https://huagongshe.com/reaction/2181262

반응식

참여 물질

역할이름HCID투입량
반응물4-Chloromethyl-2-(4-isopropyl-phenyl)-thiazoleHCID 2095697—
반응물Rac-2-ethoxy-3-(1h-indol-6-yl)-propionic acid ethyl esterHCID 69563615—
생성물Rac-2-ethoxy-3-{1-[2-(4-isopropyl-phenyl)-thiazol-4-ylmethyl]-1h-indol-6-yl}-propionic acidHCID 10456332—

반응 단계

In analogy to the procedure described in example 44, rac-2-ethoxy-3-(1H-indol-6-yl)-propionic acid ethyl ester (preparation 11) was reacted with 4-chloromethyl-2-(4-isopropyl-phenyl)-thiazole to give rac-2-ethoxy-3-{1-[2-(4-isopropyl-phenyl)-thiazol-4-ylmethyl]-1H-indol-6-yl}-propionic acid as yellow viscous oil.

출처 및 근거

DOI10.6084/m9.figshare.5104873.v1
특허 번호US06890947B2
출처 데이터셋uspto-grants-2005_05
ORD IDord-6b99233aa2be4d6781dd193b809309ec
출처 메모uspto-grants-2005_05