Potassium bis(trimethylsilyl)amide → HCID 23684418, 화합물

HRID 2181372노트

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HRID 2181372 반응식
[CH3:1][C:2]1[CH2:3][C:4]2[C:9]([CH:10]=1)=[C:8](C1C3C(=CC=CC=3)C=CC=1)[CH:7]=[CH:6][CH:5]=2.C[Si]([N-][Si](C)(C)C)(C)C.[K+:30]>C1(C)C=CC=CC=1>[CH3:10][C:2]1[CH:1]=[C:10]([C:2]2[CH-:3][C:4]3[C:9]([CH:1]=2)=[CH:8][CH:7]=[CH:6][CH:5]=3)[C:9]2[C:4](=[CH:5][CH:6]=[CH:7][CH:8]=2)[CH:3]=1.[K+:30]

참가 물질

4

반응물 2

HCID 3251421Potassium bis(trimethylsilyl)amideHCID 177791321-(2-Methyl-1H-inden-4-yl)naphthalene

생성물 1

HCID 23684418HCID 23684418, 화합물수율 228.5%

시약·촉매·용매 1

HCID 1140Toluene용매

실험 절차

2-Methyl-4-naphthylindene (1.00 g, 3.27 mmole) was dissolved in 20 ml of toluene, potassium bis(trimethylsilyl)amide (1.05 equivalent, 3.43 mmole, 0.684 g) was added and the reaction mixture was stirred at room temperature for 24 hours, during which a yellow solid precipitated. Hexane was added (20 ml) and the mixture was stirred for 2 h. The solid product was isolated by vacuum filtration through a medium porosity frit. The solid was pumped dry giving 1.10 g, 98 percent of the desired product.

후처리

  1. customprecipitated
  2. additionHexane was added (20 ml)
  3. stirringthe mixture was stirred for 2 h
  4. customThe solid product was isolated by vacuum filtration through a medium porosity frit
  5. customThe solid was pumped dry

출처 및 근거

ORD 기록
ord-63f20820a90e4fd4832188ce3a77a961
출처 데이터셋
uspto-grants-2005_05
특허 번호
US06891005B2

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