참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|
| 반응물 | Diethyl (ethoxymethylene)malonate | HCID 6871 | — |
| 반응물 | 6-Ethoxypyridin-3-amine | HCID 3040301 | — |
| 생성물 | Diethyl 6-ethoxy-3-pyridylaminomethylenemalonate | HCID 621746 | 93.7% |
반응 단계
A mixture of 2-ethoxy-5-aminopyridine (2.89 g, 20.9 mmol) and diethyl ethoxymethylenemalonate (4.23 mL, 20.9 mmol) was heated at 130° C. for 4.5 hours. While warm, the mixture was evacuated. After cooling, the product was triturated with 2:1 hexanes:ether and collected to afford 6.04 g of diethyl (2-ethoxy-5-pyridylaminomethylene)malonate as a beige solid.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 특허 번호 | US06399604B1 |
|---|
| 출처 데이터셋 | uspto-grants-2002_06 |
|---|
| ORD ID | ord-42f2437f1a6242adba650568eb28e678 |
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| 출처 메모 | uspto-grants-2002_06 |
|---|
