3-nitro-9-isopropyl-9H-carbazole → HCID 11790847, 화합물

HRID 2184931노트

반응식

HRID 2184931 반응식
[CH:1]([N:4]1[C:16]2[CH:15]=[CH:14][C:13]([N+:17]([O-])=O)=[CH:12][C:11]=2[C:10]2[C:5]1=[CH:6][CH:7]=[CH:8][CH:9]=2)([CH3:3])[CH3:2]>CCO.[Pd]>[CH:1]([N:4]1[C:16]2[CH:15]=[CH:14][C:13]([NH2:17])=[CH:12][C:11]=2[C:10]2[C:5]1=[CH:6][CH:7]=[CH:8][CH:9]=2)([CH3:3])[CH3:2]

참가 물질

4

반응물 1

HCID 6174713-nitro-9-isopropyl-9H-carbazole

생성물 1

HCID 11790847HCID 11790847, 화합물수율 98.4%

시약·촉매·용매 2

HCID 23938Palladium촉매HCID 702Ethanol용매

실험 절차

To a solution of 9-Isopropyl-3-nitro-9H-carbazole(1.5 g, 5.89 mmol) in EtOH (100 ml) was added 10% Pd-C (150 mg) and the reaction mixture was hydrogenated with a Parr hydrogenation apparatus at 45 psi H2 pressure for 3 hours. The reaction mixture was filtered and the filtrate concentrated in vacuo to afford the desired product as a solid (1.3 g, 87%).

후처리

  1. filtrationThe reaction mixture was filtered
  2. concentrationthe filtrate concentrated in vacuo

출처 및 근거

ORD 기록
ord-c589a92b2ef6434d939ce04e5de9da8e
출처 데이터셋
uspto-grants-2002_06
특허 번호
US06399631B1

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