2,2-Diphenylacetyl chloride → N-(2-Cyclopropylmethyl-2H-tetrazol-5-yl)-2,2-diphenyl-acetamide

반응식

[NH2:1][C:2]1[N:3]=[N:4][N:5]([CH2:7][CH:8]2[CH2:10][CH2:9]2)[N:6]=1.[C:11]1([CH:17]([C:21]2[CH:26]=[CH:25][CH:24]=[CH:23][CH:22]=2)[C:18](Cl)=[O:19])[CH:16]=[CH:15][CH:14]=[CH:13][CH:12]=1>>[CH:8]1([CH2:7][N:5]2[N:4]=[N:3][C:2]([NH:1][C:18](=[O:19])[CH:17]([C:11]3[CH:16]=[CH:15][CH:14]=[CH:13][CH:12]=3)[C:21]3[CH:26]=[CH:25][CH:24]=[CH:23][CH:22]=3)=[N:6]2)[CH2:10][CH2:9]1

참가 물질

반응물 2

HCID 746372,2-Diphenylacetyl chloride

HCID 224591775-amino-2-cyclopropylmethyl-2H-tetrazole

생성물 1

HCID 9858854N-(2-Cyclopropylmethyl-2H-tetrazol-5-yl)-2,2-diphenyl-acetamide

실험 절차

The title compound, white solid, m.p. 147-148° and MS: m/e=334.3 (M++H) was prepared in accordance with the general method of example 1 from 5-amino-2-cyclopropylmethyl-2H-tetrazole and diphenylacetyl chloride.

출처 및 근거

ORD 기록: ord-15dbbed72e5f441383c75609cb8147d0
출처 데이터셋: uspto-grants-2002_06
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US06399641B1

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