Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
3-Chloro-4-iodoaniline → 3-Allyl-1-(4-amino-2-chlorophenyl)piperidin-2-one
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 3-Chloro-4-iodoaniline | HCID 282926 | — |
| 반응물 | 3-Allyl-2-piperidinone | HCID 13380374 | — |
| 생성물 | 3-Allyl-1-(4-amino-2-chlorophenyl)piperidin-2-one | HCID 59586743 | — |
반응 단계
Analogously to the process described under example 93A, 6.00 g (23.7 mmol) of 3-chloro-4-iodoaniline and 4.11 g (29.6 mmol) of the compound from example 96A are used to obtain 1.57 g (25% of theory) of the title compound. The purification is effected by suction filtration using silica gel with 2:1→1:2 cyclohexane/ethyl acetate as the eluent.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08198267B2 |
| 출처 데이터셋 | uspto-grants-2012_06 |
| ORD ID | ord-1072e6521e71422e8b7d16ab4d45c732 |
| 출처 메모 | uspto-grants-2012_06 |