(Z)-3-(2,3-dimethoxyphenyl)prop-2-enoic acid → 3-(2,3-Dimethoxyphenyl)propanoic acid

HRID 2185635

반응식

HRID 2185635 반응식
[CH3:1][O:2][C:3]1[C:8]([O:9][CH3:10])=[CH:7][CH:6]=[CH:5][C:4]=1/[CH:11]=[CH:12]\[C:13]([OH:15])=[O:14].[H][H]>CO.[Pd]>[CH3:1][O:2][C:3]1[C:8]([O:9][CH3:10])=[CH:7][CH:6]=[CH:5][C:4]=1[CH2:11][CH2:12][C:13]([OH:15])=[O:14]

참가 물질

5

반응물 2

HCID 1559386(Z)-3-(2,3-dimethoxyphenyl)prop-2-enoic acidHCID 178418361HCID 178418361, 화합물

생성물 1

HCID 3149293-(2,3-Dimethoxyphenyl)propanoic acid수율 95.9%

시약·촉매·용매 2

HCID 23938Palladium촉매HCID 887Methanol용매

실험 절차

Nitrogen was passed through a stirred suspension of (Z)-3-(2,3-dimethoxyphenyl)-2-propenoic acid (14,67 g) in 400 ml of methanol during 15 minutes. Then 1.4 g of 10% palladium on activated carbon were added and a stream of hydrogen was passed through the reaction mixture for 16 hours. After removing the palladium catalyst by filtration, the filtrate was evaporated to yield 14.2 g of 3-(2,3-dimethoxyphenyl)-propanoic acid, M.S. (C.I.) (MZ): 211 [M+H]+.

후처리

  1. customAfter removing the palladium catalyst
  2. filtrationby filtration
  3. customthe filtrate was evaporated

출처 및 근거

ORD 기록
ord-a470341975dc4476a9234e11b0d07e3d
출처 데이터셋
uspto-grants-2002_06
특허 번호
US06403573B1

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