Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
p-Chlorophenacyl bromide → 5-(4-Chlorophenyl)-3,6-dihydro-1,3,4-thiadiazin-2-one
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | p-Chlorophenacyl bromide | HCID 68303 | — |
| 반응물 | O-methyl hydrazinecarbothioate | HCID 10171237 | — |
| 용매 | Acetonitrile | HCID 6342 | — |
| 생성물 | 5-(4-Chlorophenyl)-3,6-dihydro-1,3,4-thiadiazin-2-one | HCID 329473 | 48.4% |
반응 단계
A mixture of 2-bromo-p-chloroacetophenone (9.16 g), methoxythiocarbonylhydrazine (13.0 g) and acetonitrile (75 ml) was refluxed overnight and then cooled and filtered. The light yellow solid was washed with hexane and dried yielding 5-(4-chlorophenyl)-3H,6H-1,3,4-thiadiazin-2-one (4.3 g).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05728715 |
| 출처 데이터셋 | uspto-grants-1998_03 |
| ORD ID | ord-78ffab45f98b4d54bbf0b4abd3bad247 |
| 출처 메모 | uspto-grants-1998_03 |