참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|
| 반응물 | p-Chlorothiophenol | HCID 7815 | — |
| 반응물 | Potassium Carbonate | HCID 11430 | — |
| 반응물 | 2-Bromo-4'-methylacetophenone | HCID 69272 | — |
| 용매 | Dimethylformamide | HCID 6228 | — |
| 생성물 | 2-(4-Chlorophenylthio)-1-(4-methylphenyl)ethanone | HCID 2745101 | 82.3% |
반응 단계
A mixture of 10.0 g (47 mmol) 4-methylphenacyl bromide, 6.8 g (47 mmol) 4-chlorothiophenol, and 6.5 g (47 mmol) anhydrous potassium carbonate in 100 ml dry DMF was stirred for 3 h at 80° C. It was filtered and the filtrate was concentrated under reduced pressure. The concentrate was stirred in water, and the resulting solid was filtered off, washed with water, and recrystallized from ethanol to give 10.7 g (82%) of the crude title compound.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 특허 번호 | US06410562B1 |
|---|
| 출처 데이터셋 | uspto-grants-2002_06 |
|---|
| ORD ID | ord-44f50bf5ebd84717b40adb93417d9ac3 |
|---|
| 출처 메모 | uspto-grants-2002_06 |
|---|
