Thionyl Chloride → 1-(4-Methoxyphenyl)-2,2-dimethylcyclopropanecarbonyl chloride
반응식
[CH3:1][O:2][C:3]1[CH:8]=[CH:7][C:6]([C:9]2([C:14]([OH:16])=O)[CH2:11][C:10]2([CH3:13])[CH3:12])=[CH:5][CH:4]=1.S(Cl)([Cl:19])=O>CN(C=O)C>[CH3:1][O:2][C:3]1[CH:8]=[CH:7][C:6]([C:9]2([C:14]([Cl:19])=[O:16])[CH2:11][C:10]2([CH3:13])[CH3:12])=[CH:5][CH:4]=1참가 물질
4
실험 절차
A mixture of 1-(4-methoxyphenyl)-2,2-dimethylcyclopropanecarboxylic acid (44 mg, 0.20 mmol), thionyl chloride (44 μL, 0.60 mmol) and DMF (1 drop) was stirred at room temperature for 30 minutes. The mixture was concentrated and the resultant acid chloride was used without further purification.
후처리
- concentrationThe mixture was concentrated
- customthe resultant acid chloride was used without further purification
출처 및 근거
- ORD 기록
- ord-b9be44101d3b49a3b6ab3ddfdd29b7d3
- 출처 데이터셋
- uspto-grants-2012_12
- 특허 번호
- US08324207B2
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