Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
4-Amino-1-butanol → 3-[(2-fluoro-4-iodophenyl)amino]-N-(4-hydroxybutyl)isonicotinamide
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 4-Amino-1-butanol | HCID 25868 | — |
| 반응물 | 3-((2-Fluoro-4-iodophenyl)amino)isonicotinic acid | HCID 59026791 | — |
| 생성물 | 3-[(2-fluoro-4-iodophenyl)amino]-N-(4-hydroxybutyl)isonicotinamide | HCID 11611678 | — |
반응 단계
3-[(2-fluoro-4-iodophenyl)amino]-N-(4-hydroxybutyl)isonicotinamide was synthesized according to the procedure for General Method 1, outlined above, starting with 0.5 mmol of 3-[(2-fluoro-4-iodophenyl)amino]isonicotinic acid (intermediate 1) and 0.63 mmol of 4-hydroxy-butylamine. LC/MS [8.42 min; 430 (M+1)]
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08198457B2 |
| 출처 데이터셋 | uspto-grants-2012_06 |
| ORD ID | ord-1c6022afebca4a0eade982d4e5f2fd68 |
| 출처 메모 | uspto-grants-2012_06 |