참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|
| 반응물 | 2,4,6-Tribromophenol | HCID 1483 | — |
| 반응물 | Dimethylformamide | HCID 6228 | — |
| 반응물 | Chloroacetone | HCID 6571 | — |
| 반응물 | Potassium Carbonate | HCID 11430 | — |
| 용매 | Water | HCID 962 | — |
| 생성물 | 2,4,6-Tribromophenoxyacetone | HCID 3303004 | 97% |
반응 단계
A mixture of 5 g 2,4,6-tribromophenol (15 mmol), 1.4 g 1-chloroacetone (15 mmol), 4.16 g anhydrous potassium carbonate (30 mmol) and 20 ml DMF is stirred at 27° C. Completion of the reaction is confirmed by TLC. The reaction mass is diluted with water and extracted with ethylacetate The organic layer is washed with water and brine, dried over anhydrous sodium sulphate and concentrated to obtain 5.6 g 1-(2,4,6-tribromo-phenoxy)-propan-2-one (97%).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 특허 번호 | US08324263B2 |
|---|
| 출처 데이터셋 | uspto-grants-2012_12 |
|---|
| ORD ID | ord-38af585a78e94ac3a9c44895c8a11a23 |
|---|
| 출처 메모 | uspto-grants-2012_12 |
|---|
