Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
tert-Butyl piperazine-1-carboxylate → N-(3-tert-Butyl-phenyl)-2-fluoro-4-piperazin-1-yl-benzamide
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | tert-Butyl piperazine-1-carboxylate | HCID 143452 | — |
| 반응물 | 4-Bromo-N-(3-tert-butyl-phenyl)-2-fluoro-benzamide | HCID 59317996 | — |
| 반응물 | N-(3-tert-Butyl-phenyl)-3-fluoro-4-piperazin-1-yl-benzamide | HCID 59318037 | — |
| 생성물 | N-(3-tert-Butyl-phenyl)-2-fluoro-4-piperazin-1-yl-benzamide | HCID 59318090 | — |
반응 단계
N-(3-tert-Butyl-phenyl)-2-fluoro-4-piperazin-1-yl-benzamide was synthesized from 4-bromo-N-(3-tert-butyl-phenyl)-2-fluoro-benzamide and piperazine-1-carboxylic acid tert-butyl ester in a manner similar to the one described in the synthesis of N-(3-tert-butyl-phenyl)-3-fluoro-4-piperazin-1-yl-benzamide above. LCMS calcd for C21H26FN3O (m/e) 355, obsd 356 (M+H).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08324385B2 |
| 출처 데이터셋 | uspto-grants-2012_12 |
| ORD ID | ord-d84bfd0ce27e457abed0cbdef09f2850 |
| 출처 메모 | uspto-grants-2012_12 |